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More hcv inhibitor protease Results:

HIV/HCV coinfection and protease inhibitor treatment increase hyperglycemia risk
An HIV treatment news story from AIDSmeds.com. ... and hepatitis C virus (HCV) coinfection with protease inhibitor (PI) treatment increases the risk ...
http://www.aidsmeds.com/news/20030828clin005.html

Hepatitis C Research
... investigational hepatitis C viral (HCV) protease inhibitor VX-950 exhibits potent and ... resistant to another investigational HCV protease inhibitor currently being developed by ...
http://www.janis7hepc.com/hepatitis_c_research31.htm

Vertex Pharmaceuticals Press Release January 2, 2003
... studies with another company’s HCV protease inhibitor compound have established initial ... anticipate that Vertex’s ongoing HCV protease inhibitor discovery program will produce ...
http://www.vpharm.com/Pressreleases2003/pr010203.html

HIV-HCV Coinfection and Protease Inhibitor Treatment Increase Hyperglycemia Risk
... HIV-HCV Coinfection and Protease Inhibitor Treatment Increase Hyperglycemia Risk ... and hepatitis C virus (HCV) coinfection with protease inhibitor (PI) treatment increases the risk ...
http://www.hivandhepatitis.com/hiv_hcv_co_inf/082903a.html

Protein Engineering, Design and Selection -- Martin et al. 12 (11): 1005
... A loop-mimetic inhibitor of the HCV-NS3 protease derived from a minibody ... a competitiverather than a noncompetitive inhibitor of the protease as sucha compound will be less ...
http://protein.oupjournals.org/cgi/content/full/12/11/1005

JVI -- Trozzi et al. 77 (6): 3669
... The hepatitis C virus (HCV) serine protease is necessary forviral ... the use HCV subgenomic replicons to isolate and characterizemutants resistant to a protease inhibitor. Taking ...
http://jvi.asm.org/cgi/content/full/77/6/3669

JBC -- Pause et al. 278 (22): 20374
... The effect of this potent NS3 protease inhibitorwas evaluated on replication of subgenomic HCV RNA and compared ... A, a hexapeptide-like inhibitor of HCV NS3 protease. B, a series ...
http://www.jbc.org/cgi/content/full/278/22/20374

Hepatitis C Protease Inhibitor Developed...inhibitor for the potential treatment of hepatitis C ...

http://rdre1.yahoo.com/click?u=http://www.highbeam.com/library/doc0.asp%253Fdocid%253D1P1:49900202%2526refid%253Dink_overture_hlth%2526skeyword%253Dhepatitis%2526teaser%253D...inhibitor%252Bfor%252Bthe%252Bpotential%252Btreatment%252Bof%252Bhepatitis%252BC%252Bvirus%252B(HCV)%252Binfection%252Bas%252Ba%252Bdevelopment...antiviral%252Bdrugs%252Bbeing%252Bstudied%252Bto%252Binhibit%252Bhepatitis%252BC%252BNS3-4A%252Bprotease%252Ban%252Benzyme%252Bconsidered...p/%252Bp/%252BAuthor%252Bnot%252Bavailable%252Bi%252BHepatitis%252BC%252BProtease%252BInhibitor%252BDeveloped/i...%26y=0247E308CB0258FD%26i=487%26c=4786%26q=02%255ESSHPM%255BL7w%257Ci%253Fvqwv%257Dvkpm%253Fompkz~lz6%26e=utf-8%26r=18%26d=nrm-en-us%26n=EB6K5H58TMH400JO%26s=8%26t=%26m=40A2F964%26x=01F47A3E92E08A33

Vertex Pharmaceuticals Restructures Agreement with Eli Lilly; Vertex to Lead Development of Novel Oral Hepatitis C Prote
... Obtaining worldwide rights to our HCV protease inhibitor program is an important value creation step ... the value of our HCV protease inhibitor discovery program," said Joshua Boger ...
http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104%26STORY=/www/story/01-02-2003/0001865127%26EDATE=

HispanicPRWire - Schering-Plough Reports Novel Investigational Protease Inhibitor Shows in Vitro Antiviral Activity in H
Schering-Plough Reports Novel Investigational Protease Inhibitor Shows in Vitro Antiviral Activity in Hepatitis C Infection. BOSTON,--(HISPANIC PR WIRE)--Oct. ... Schering-Plough has a dedicated HCV protease inhibitor development program ... assess the antiviral activity of a novel protease inhibitor in the Schering-Plough portfolio known as SCH6 ...
http://www.hispanicprwire.com/print_in.php?id=1606%26cha=9

Vertex Pharmaceuticals Press Release October 27, 2003
Research Findings Suggest Potent Antiviral Activity and Favorable In Vitro Resistance Profile for Vertex’s Investigational HCV Protease Inhibitor VX-950. Boston, MA, October 27, 2003 -- ... investigational hepatitis C viral (HCV) protease inhibitor VX-950 exhibits potent and ... resistant to another investigational HCV protease inhibitor currently being developed by ...
http://www.vpharm.com/Pressreleases2003/pr102703.html

New Drugs in Development for the Treatment of Chronic Hepatitis C
... These include an HCV protease inhibitor (BILN 2061), a fusion protein (albuferon), a monoclonal antibody (HCV-AB68), and an HCV antisense inhibitor (Isis 14803). One ...
http://www.hivandhepatitis.com/hep_c/news/011003a.html

HIV Report Jan 2003: A Promising New Anti-HCV Protease Inhibitor
... A Promising New Anti-HCV Protease Inhibitor. By Mark Sulkowski, M.D. ... safety and early antiviral activity of BILN 2061, a serine protease inhibitor [Hepatology 2002;36:167A]. ...
http://www.hopkins-aids.edu/publications/report/jan03_4.html

CAMBRIDGE, Mass
... to our HCV protease inhibitor program is an important value creation step and ... value of our HCV protease inhibitor discovery program," said Joshua Boger, ...
http://www.hepatitisresources-calif.org/news/010203%2520Vertex%2520oral%2520protease.htm

HCV Protease Inhibitors: Vertex VX-950 clinical trial in 2003
... Obtaining worldwide rights to our HCV protease inhibitor program is an important value creation step ... the value of our HCV protease inhibitor discovery program," said Joshua Boger ...
http://www.natap.org/2003/Jan/010103_5.htm

EMBOJ -- Barbato et al. 19 (6): 1195
... Inhibitor binding induces active site stabilization of the HCV NS3 protein serine protease domain ... among the serine protease family: theserine protease domain is covalently attached ...
http://www.emboj.org/cgi/content/full/19/6/1195

HIV Report Nov 98 - HIV and Hepatitis C Virus Co-infection
... Protease Inhibitor Associated Hepatotoxicity: Role of HCV? Hepatitis C Viremia and Disease Activity: Impact of HAART and HIV Co-infection. HCV and HIV Co-infection: Clinical Outcomes ...
http://www.hopkins-aids.edu/publications/report/nov98_5.html

1st HCV protease Inhibitor: effective over 2-day study
Conference Reports for NATAP. AASLD (American Association for the Study of Liver Diseases)& nbsp. Nov 2-5, 2002, Boston, MA. Back . 1st HCV protease Inhibitor: effective over 2-day study. Reported by Jules Levin ... results where HCV+ patients received the HCV protease inhibitor. Patients have chronic HCV, genotype 1, and ...
http://www.natap.org/2002/AASLD/day7.htm

Enzim Helikase sebagai Target Obat Antivirus - Jumat, 18 Juli 2003
... hepatitis C (HCV) juga terfokus pada usaha penemuan inhibitor protease. Selama ini berbagai senyawa kandidat inhibitor protease dari HCV sudah ditemukan, namun baru ...
http://www.kompas.com/kompas-cetak/0307/18/inspirasi/438682.htm

January 2003 News Bites
... studies with another company's HCV protease inhibitor compound have established initial proof ... anticipate that Vertex's ongoing HCV protease inhibitor discovery program will produce ...
http://www.askemilyss.com/bites/bite0103/vrtx.htm